SOLUBILITY TEST
BMG LABTECHNOLOGIES
SOLUBILITY LAYOUT
PLATE 1
1999.08.10
19:48
30
0000
0012
NG 4.00-1
GROUP FUNCTION
4 GROUPS
2002.05.28
16:46:02
084
NG 4.30-0
SEGMENTAL REGR
DILUTION
SEGM. REGR. EXAMPLE
2002.06.26
20:18:37
021
SILICA DILUTION
LABSYSTEMS CLINIPLAT
initial clin. plate
2010/06/28
12:06:54
030
CAL TEST PLATE 60722
Univ Tesp Plate 6072
11:33:02
000
TEST PLATE 60722
cal plate 96 60722
11:45:04
128
PE Multilabel 259948
11:56:26
curadev
2010/10/04
16:14:51
149
curradev test
2010/12/18
16:58:22
coffee
181210
Test cc plate
2011/02/19
11:56:39
11:57:17
11:58:44
100
12:00:29
laser 3.5
12:01:23
laser 1.5
12:02:21
150
gain 150
12:03:04
120
gain 120
12:03:51
110
gain 110
IBS cpd_190211
12:20:56
12:21:49
12:24:42
IBS cpd_2nd batch
2011/02/21
12:02:41
220211
12:04:25
edta removed
12:16:23
23,24,25
12:18:50
23,24,25 n2
12:29:08
23,24,25 n3
12:36:50
23,24,25 n4
12:46:56
23,24,25 n5
12:47:57
IBS cpd_3rd batch
14:49:11
14:50:37
14:54:20
EDTA
test
15:13:30
CRD22,23,24,25
18:47:58
100µM & 20µM
IBS batch4
2011/02/23
12:21:56
Sial
instrument chek
2011/02/25
11:49:55
test run
12:12:52
Enamine
2011/03/18
15:04:07
CRD30-42
15:06:26
n2
15:16:54
AAAC
CRD30,31,34,36
2011/03/21
11:35:06
CRD39,40,41,42
100 & 20uM
11:38:54
11:42:56
100 & 20uM n3
11:47:00
100 & 20uM n4
W/O spin & spin
2011/03/31
11:59:18
20uM solubility
CRD
12:03:08
CRD n2
13:53:47
CRD32 33 35 37 38
42 acylo biotin
CRD23 24 & 41
2011/04/01
15:06:40
20 & 5uM
with & w/o spin
15:08:55
with & w/o spin n2
CRD23 24 & 41 _TEST
15:12:09
CRD23 24 & 41 _N plt
15:18:39
15:22:04
CRD7,8,21,22,23,24
2011/04/08
14:48:58
25,40,41,42
100 & 20uM_1% & 0.5%
14:52:50
CRD43 to 64 at 20uM
2011/05/09
14:33:25
1%DMSO CRD23 & 24 B2
15:02:29
58,60,61 at 5uM
43,45,50,51,53,54,57
CRD 66- CRD72_cp com
2011/05/10
13:56:22
JAK
CDV03
13:58:50
14:23:28
14:25:09
14:29:20
JAK _plate change
14:31:34
CDV03 final
CRD74 & 75
2011/05/13
12:13:38
20, 5 & 1uM
1% DMSO
12:22:38
1% DMSO greiner
CRD74-75
2011/05/14
13:14:18
100µM and 20µM
13:23:00
CRD76,77,78,79
2011/05/18
13:16:57
check
CRD80 to 85
2011/05/26
11:46:05
20uM 1% DMSO
11:58:11
N2
12:03:13
N3
12:15:48
CRD82 20uM & 5uM
CRD70,71,72 100uM
2011/05/27
15:57:28
CRD86 to 93
2011/06/01
12:59:05
20uM and 0.5uM
1% DMSO buffer
13:00:59
1% DMSO buffer N2
13:13:24
20uM 0.5uM and 10uM
CRD24,81,88
2011/06/02
13:08:21
100uM,31.6um & 10uM
CRD74 to 93
2011/06/03
16:29:36
20uM & 10uM
16:34:19
N2 final
17:49:35
final
CRD94 to 102
2011/06/08
12:54:02
20uM,10uM & 5uM
CRD103 to 145
2011/06/13
12:59:45
20uM
CRD146 to 149
2011/06/16
12:55:21
CRD156 to CRD162
2011/06/30
11:32:11
10uM & 1uM
11:35:29
1% DMSO buffer N1
CRD157,158,161 &162
2011/07/04
14:55:04
100uM & 31.6uM
15:00:36
CRD182
2011/07/28
11:16:01
100uM, 31.6uM, 10uM
CRD187 & 188
2011/08/01
11:53:31
100uM 4dilution 3.16
13:07:06
2hr
13:08:27
CRD189 to 197
2011/08/11
17:00:30
100uM
17:04:09
CRD208,215,209,219 &
2011/08/23
13:01:48
220
1%DMSO PBS
13:02:21
1%DMSO PBS 20uM
13:05:22
1%DMSO PBS 20uM N3
13:07:12
1%DMSO PBS 20uM N4
13:07:58
1%DMSO PBS20uM final
CRD223,224,225
2011/08/29
13:35:33
1%DMSO 20uM
13:36:39
1%DMSO 20uM N1
CRD226,227,228,229
2011/08/31
11:56:17
CRD230,231,232
1%DMSO 100uM 0hr
11:58:04
1%DMSO 100uM 0hr N1
CRD208-221
2011/09/04
16:35:33
2fold 4dilution
1%DMSO PBS 100uM
16:38:45
2fold 4dilution  N2
CRD233 - 238
2011/09/12
10:46:13
100uM & 20uM
1%DMSO
10:48:36
1%DMSO 2nd read
10:51:10
1%DMSO 3rd read
15:34:25
1%DMSO 4hr
Incyte 1mM
2011/09/14
14:33:48
sonicated & tritonX
C
CRD150 to 155
2011/09/20
14:47:35
1%DMSO buffer
14:49:20
1%DMSO buffer N2
CRD163 to 168
14:50:23
14:51:12
CRD169 to 176
14:52:31
14:53:57
CRD177 to 186
14:57:07
14:58:10
CRD198 to 207
15:01:39
15:09:30
SOLUBILITY
Nife
2011/09/28
11:24:03
pH 3
11:25:20
11:27:04
183
11:27:56
152
nife
11:28:44
ph 3
11:30:14
ph3
11:31:23
11:36:04
11:38:34
11:39:19
11:49:46
nife 100ug/ml
19:37:32
Kinetic , ph3
19:38:55
Nifedipine
19:46:32
Aqua, pH3
19:47:54
2011/09/30
11:08:02
pH 7.4
11:11:18
11:12:55
11:13:37
11:17:17
more cntrl
16:32:16
pH 9
16:34:46
16:39:58
CRD279 to 296
2011/10/12
15:45:39
15:50:51
1%DMSO buffer 2nd
15:56:23
20uM final
CRD297 to 300
2011/10/17
14:46:57
100 & 31.6uM
14:49:12
CRD303 to 309
2011/10/18
13:13:27
13:15:08
CRD313 to 322
2011/10/24
14:19:43
14:21:40
CRD322 to 339
2011/11/01
12:10:17
12:13:23
12:21:09
1%DMSO buffer 3rd
12:25:48
1%DMSO buffer 4th
CRD336 & 339
2011/11/04
100_50_20uM
1% 2% DMSO_ACN_EtOH
13:06:26
100_50_20uM_2nd
13:24:11
100_50_20uM_3rd
CRD236 brij conc
17:51:57
17:54:57
CRD340 to 362
2011/11/07
13:41:47
13:44:09
20uM_n=2
15:07:32
20uM, 10uM & 5uM
2011/11/12
17:49:44
DMSO1%
nife_acn_ph3_ph7.4
2011/11/14
19:11:41
ph9 solubility 14111
19:58:08
CRD363 to 366 _319B2
2011/11/15
17:35:18
20uM & 2uM
CRD334
17:51:37
31.6uM to 0.316uM
CRD369 to 393
2011/11/21
18:40:45
CRD353 to 360
2011/11/22
15:07:16
50 & 20uM
CAL
2011/11/25
15:01:14
255
15:02:47
20:13:55
20:15:55
Incyte solubility
2011/11/28
19:58:15
1.6mg/ml serial
2fold in pH7.4
20:01:08
20:05:39
2fold in pH7.4 3.5fo
20:07:29
025
25gain
20:09:41
091
20:11:04
075
20:12:07
080
20:13:33
20:15:38
final pH7.4
2011/11/29
13:37:38
pH3,7.4,9
13:40:33
090
14:33:24
Incyte thermodynamic
2011/11/30
10:59:26
1.0mg/ml serial
11:03:20
11:05:58
solubility_incyte_1h
13:18:35
buffer_30.11.11
Incyte_thermodynamic
13:25:08
read after 1hr
pH3,7.4, 9
15:22:46
after 1h centrifuged
Incyte_Formu_301111
20:27:11
Incyt_Formu_301111
20:29:30
20:31:14
20:33:08
20:34:27
20:40:36
085
Incyte_Formulation
20:45:28
301111
Tw80,PG,PEG,Gly
20:47:43
301111_final
CRD394 to 402 &325B2
20:51:01
20 & 2uM
20:53:39
20 & 2uM final
Incyte_Formu
21:05:40
301111_Centrifuge
t80,pg,peg,glyce
21:07:58
21:08:25
21:18:52
301111_Centri_final
Tween_Scattering
2011/12/01
12:28:46
Instant_Centri
12:29:58
12:31:13
011211
12:31:55
011211 final
incyte_pref_ON_centr
19:39:55
t80,peg,pg,gly_11211
19:44:11
2 read
19:54:22
3 read
19:56:37
4 read
20:00:57
Formu_Re_Tween_PEG20
2011/12/02
18:07:24
Solubility
18:08:50
18:14:36
gain 90
18:16:50
gain_100_final
18:33:22
Inst_Centri_011211
gain_100
18:38:20
gain_100_Final
Tween_Point5%_PEG20
19:26:06
19:32:45
Inst_011211
19:45:37
gain_100_fijnal
Tween_Point5%
20:09:52
20:10:44
gain_90_fijnal
20:20:14
CRD361 to 376 & 403
2011/12/03
13:02:37
404, 50µM & 20µM
031211
CRD403, 404
2011/12/06
15:47:12
50µM 2fold upto 8 X
6.12.11
solubility test
18:31:12
CRD377 to 384, 50 &
20µM; code1,2. 505
CRD37 to 384,50µM,20
18:45:54
code1,2, 505,50µg/ml
10µg/ml;5.12.11
CRD 385 to392
2011/12/09
16:08:45
50µM & 20µM
9.12.11
CRD-414_kinetic_
2011/12/12
20:25:15
ph3_ph9_121211
20:26:57
20:40:05
21:14:54
21:15:39
2011/12/13
12:37:29
ph3_ph9_131211
CRD-414_kinetic
12:43:15
12:45:42
12:48:42
12:51:00
12:52:02
12:53:16
5 reading
12:58:20
final_gain 90
13:01:32
gain 90_final2
13:08:38
gain_80_final
20:20:19
last 2 dilu
20:21:16
last 2 dillu_final
CRD_ph12
2011/12/15
14:18:13
CRD414_pH_2_10_12
14:27:53
Kinetic_625
MicroM_151211
14:29:44
MicroM_151211_2
14:31:25
15:01:08
MicroM_151211_Final
15:04:11
MicroM_151211_Final2
15:06:36
MicroM_151211_Final3
15:10:32
MicroM_151211_Final4
15:13:20
115
_151211_gain_115
15:15:10
CRD 401 to 411
2011/12/16
14:48:50
50 & 20 µM
16.12.11
CRD 401 to 411 new
14:56:35
50 and 20 µM
401 t0 411
15:07:25
50 & 20 uM
15:10:01
401 to 404
15:46:18
2011/12/21
13:22:33
CRD 409 to 417
2011/12/23
15:02:49
except 414
50 & 20µM 23.12.11
CRD 409 t0 407
15:09:04
50uM & 20uM
CRD418 to 426
16:02:45
23.12.11
CRD427-428 50&20uM
2012/01/20
13:12:50
20.1.12
CRD427-448
13:16:08
13:23:27
50 & 20µM
CRD449 & 450
13:29:10
449 & 450
13:32:56
CRD278-298
19:12:13
CRD 443-450
19:19:58
CRD443-450
19:26:20
50um & 20uM
Praz,Yoh,1807_100uM,
19:47:28
30 &10uM; CRD425&426
100,50,20uM
2012/01/23
10:41:56
CRD 261-280 w/o 269
2012/02/13
17:49:13
18:03:48
13.2.12
CRD451 to 469
18:52:32
19:00:44
19:03:33
13.2.12 a
yohimbine in KP04
2012/02/14
10:19:53
100,50,20µM
10:23:49
14.2.12
10:26:54
14.2.12 a
10:29:10
14.2.12 b
10:31:29
14.2.12 c
10:35:29
14.2.12 d
11:10:22
100, 50, 20µM tripli
11:13:09
14.2.12 re
CRD347
2012/02/15
15:52:58
CRD483-497
17:32:39
triplicates
Check
17:57:44
17:58:55
CRD470-482
2012/02/22
18:22:07
CRD498-512
2012/02/25
13:30:07
25.2.12
MDV1400
2012/03/02
12:10:27
100,50,20 & 10µM
2.3.12
12:53:31
30 min icubation
2012/03/03
14:58:14
N
15:26:16
0 min_3.3.12
15:56:15
30 min_3.3.12
16:32:31
60 min_3.3.12
16:56:01
90 min_3.3.12
17:29:48
120 min_3.3.12
18:03:19
150 min_3.3.12
18:25:11
180 min_3.3.12
MDV1400 in 0.5%DMSO
2012/03/05
11:37:56
50,20 & 10µM
0 min_5.3.12
12:06:28
30 min_5.3.12
12:36:12
60 min_5.3.12
13:05:54
150 min_5.3.12
CRD513-524 & 486
2012/03/06
12:14:10
50,20 & 2µM
6.3.12
17:51:07
5h incubation
CRD 334 in ACN
2012/03/07
13:45:00
50µM 2fold upto _12X
0 min
14:17:23
30 min
14:37:25
45 min
14:48:16
60 min
15:17:58
90 min
15:46:44
120 min
16:18:10
150 min
16:44:43
180 min
CRD 298-313
2012/03/09
17:35:34
w/o 301& 302
50,20 & 2µM_9.3.12
17:40:58
50,20 & 2µM_9.03.12
18:04:32
w/o 301& 302 new
CRD 304 & 312
18:16:34
20uM_2 fold_upto 7X
9.03.12
CRD 314-321
18:51:41
9.3.12
CRD322-336
2012/03/12
10:54:59
12.3.12
11:09:56
15 min incubation
CRD 525-530
13:24:44
14:06:40
30min
CRD 531-534
2012/03/13
12:12:58
13.3.12
CRD 253-260
12:14:57
12:34:01
15 min
12:40:37
CRD 236-238
2012/03/16
15:13:34
10 min
CRD 245-252
15:15:53
16.3.12
15:18:17
16.03.12
CRD 240-244
16:16:17
CRD 535-542
2012/03/19
12:25:30
19.03.12
12:55:29
13:20:36
CRD 526-531,538-541
2012/03/22
13:26:55
IC50 dil
0min
13:56:09
14:45:03
70min
CRD 543-547
2012/03/23
11:54:42
50,20,10 & 2µM
11:56:56
23.3.12
12:32:30
CRD 548-553
2012/03/26
12:12:11
12:40:07
CRD 168-175
2012/03/27
16:15:05
16:51:35
CRD 184-192
18:35:18
CRD 176-183
18:39:43
CRD 192-199
2012/03/28
17:31:17
CRD 200-207
17:33:49
17:38:43
20min
17:41:18
CRD 208-216 w/o 214
17:46:19
CRD 223-230
17:50:24
CRD554-565
2012/04/04
17:43:53
CRD136-150
2012/04/05
15:56:39
16:03:06
CRD151-165
16:49:44
CRD 566-569
2012/04/10
16:03:34
16:06:59
50, 20 & 2µM
10.4.12
CRD 486 batch-2
2012/04/16
18:45:50
50, 20,10 & 2µM
CRD 570-585
2012/04/17
15:30:38
15:42:08
17.4.12
15:47:26
17.04.12
CRD 587-590
2012/04/20
16:50:34
CRD 587-591
16:54:11
20.4.12
16:58:19
20.04.12
CRD 592-598,
2012/04/21
17:09:07
434batch-2,577 & 586
pacltaxel
2012/05/04
19:17:54
100µM_2fold
pacltaxel formulated
2012/05/07
19:18:57
7.16µM_10fold
Doxorubicin in NSS
2012/05/11
13:28:21
50µM_2fold
14:36:33
60min
CRD599-610
18:28:28
50,20, & 2µM
18:42:09
11-05-12
(-)NE_100 & 1%DMSO,
2012/05/14
18:39:00
acid stock_100µM_
3fold_0 min
19:01:00
3fold_30min
19:15:30
3fold_45min
19:31:09
3fold_60min
19:46:22
3fold_75min
20:06:31
3fold_90min
CRD601-615
2012/05/21
15:04:08
CRD616-627
16:43:00
CRD628-632
16:46:37
CRD633-647
2012/06/05
17:19:02
17:22:43
CRD648
17:26:42
17:28:04
CRD 592,601-620 &
2012/06/08
19:51:09
592 B2
30µM pH-4
19:54:23
30µM pH-7.4
19:56:54
CRD 621-650
2012/06/10
14:26:52
14:30:43
14:34:50
14:37:33
CRD 651-658
15:02:08
592 B3 & 611 B2
15:03:31
15:06:16
15:07:41
15:09:49
CRD 592,601-620
2012/06/11
14:48:32
14:50:34
CRD592b2 & 633b2
2012/06/15
16:00:15
100µM_2 fold_5diln
100mM PO4 BUFFER
16:03:12
16:07:32
16:12:06
CRD656-672
2012/06/26
18:51:59
18:56:00
CRD673-675
18:58:56
CRD659-675
2012/06/28
17:39:33
30µM
pH-4.0
17:43:54
17:47:43
pH-7.4
17:53:18
CRD676-681
2012/07/02
18:27:02
MDV2335 & 2357
2012/07/09
15:54:39
50,30,10µM half log
MDCP185, 207, 258
15:58:31
10µM half log
16:21:51
MDV2335 &2357
16:24:53
16:58:05
17:25:09
MDCP185,207,258,Ver
17:31:59
MDCP185,207,258,Vor
17:49:05
(PBS) 10µM half log
18:14:46
18:22:48
30 min _change
CRD682-693
2012/07/11
13:05:24
13:10:14
CRD658-687
2012/07/18
12:39:01
12:44:31
12:48:22
12:53:40
pH-7.4 old protocol
13:00:13
13:03:20
A1B_A2A_assay buffer
13:09:48
PBS, water
13:11:34
13:15:09
13:26:16
A1B_A2A_binding bufr
14:01:54
PBS,water
14:18:11
water
CRD694,695
14:26:25
50,20,2uM
SK
A1B_A2A_Bindng bufr
14:28:38
CRD-694,695
14:34:34
MDV1806, 1807
15:51:38
(salt, free base)
100µM-1/2log
16:03:59
17:03:19
17:16:23
(salt, free base) n2
CRD694-704
2012/07/23
16:43:51
17:01:04
17:04:45
CRD688-703
2012/07/24
13:56:33
30uM
pH-4
13:59:25
MDPC258
2012/08/03
14:45:19
100µM_half log_10dil
15:15:49
15:46:57
16:15:14
90min
16:49:42
120min
17:20:43
180min
17:44:50
240min
Cyclophosphamide,Dox
2012/08/08
15:54:38
& paclitaxel(DMSO)
100µM_2fold_8diln
16:01:26
MDV2395
2012/08/27
11:41:42
50,30,10,3µM...
11:48:36
12:18:26
CRD-704-718
2012/08/29
13:37:08
13:38:42
CRD-719-730
13:42:51
CRD722, 726 & 728
2012/08/31
16:08:22
10µM_2fold_in NaPo4
pH-3 & 8_0min
16:41:02
10µM_2fold_in NaPO4
pH-3 & 8_0min_65C
16:44:54
pH-3 & 8_30min_37C
17:12:48
pH-3 & 8_30min_65C
17:16:33
pH-3 & 8_60min_37C
17:44:59
pH-3 & 8_60min_65C
solubility
2012/10/04
11:52:38
CRD751-752_Nutlin-3a
50_20_2um
11:54:37
MDV2508
2012/10/08
10:51:33
50,30,10,3µM in PBS
0  min
11:09:06
hrishitaCRD736-746
2012/10/09
19:14:17
50,20,10,2uM
91012
20:15:43
91012 30min
20:21:00
solubility hri
2012/10/10
crd736-746_16hrs
50_30_20_2uM_91012
CRD757-CRD767
2012/10/23
18:05:18
100_50_20_2 uM conc.
231012
CRD768-CRD778
18:09:53
2012/11/07
15:35:07
CRD779-CRD793
50_20_2uM
2012/11/12
14:17:21
CRD633_672_759
100uM_2fold_6diln.
14:55:33
2012/11/17
11:52:55
PCI32765
2012/12/01
16:14:38
CRD790-CRD804
16:18:21
CRD805-CRD819
2012/12/03
17:23:31
CRD820-CRD834